Glucose Balance Across the Body
Hepatocytes, unique in their dual ability to both store and release glucose, rely on insulin and serotonin for balanced function. Disruptions lead to fluctuating glucose levels, causing hyperglycemia and hypoglycemia.
Central Role in Lipid Regulation
Acting as the chief hub for lipoprotein processes, hepatocytes manage lipid uptake, formation, and release into circulation. Common diseases like Dyslipidemia disrupt hepatocyte lipid metabolism leading to chronic conditions like NAFLD.
HDV can be customized to target drug payloads to hepatocyte cells, whether injected or taken orally.
HDV is designed to be accepted and removed by the liver through normal liver metabolism.
Pristine safety profile in ~350 human exposures to date with injectable and oral dosing.